Farnesyltransferase Inhibitors in Cancer Therapy 87 Uganda / RIGBY

Uganda / RIGBY

and discuss experimental and computational approaches

Michel -- Part III

die sie mir bei der vorliegenden wie bei anderen Arbeiten immer wieder zu Teil werden lieBen

Seminar paper from the year 2006 in the subject Computer Science - Commercial Information Technology

Farnesyltransferase Inhibitors in Cancer Therapy 87 Uganda / RIGBYCutting edge researchers describe their efforts to design, synthesize, and evaluate the biological activities of farensyltransferase inhibitors (FTIs); geranylgeranyltransferase inhibitors (GGTIs) are also discussed as potential anticancer drugs. The authors survey in detail such inhibitors as CAAX box peptidomimetics, FPP mimics, and bisubstrate transition state analogs, and critically review their uses in combination with radiation and other